Rejection Sensitivity Dysphoria

What is Rejection Sensitivity Dysphoria? And How to Tell if You May Have it

Many people have been identifying with something called “Rejection Sensitivity Dysphoria”, otherwise known as RSD. Although it isn’t officially a medical diagnosis as of right now, it is a way of describing a certain type of emotional dysregulation, specifically pertaining to rejection and failure.

What is RSD?

RSD is defined as feeling severe emotional pain as a result of feeling rejected or like a failure, and is most commonly recognized in people with ADHD, however it can also occur in people with mood disorders. Although there’s still very little evidence on RSD, researchers have discovered that RSD may occur due to brain structures being unable to regulate emotions properly in neurodivergent folks.

What are the symptoms of RSD?

Although everyone is different, people with RSD may feel embarrassed easily, show low self esteem, feel anger, or experience extreme sadness when feeling rejected. They also identify as being “people pleasers” in order to avoid feeling rejected by others, and avoid starting projects if feel like they may fail. Another characteristic of RSD is that people may strive for perfectionism in order to avoid failure and rejection. Additionally, some people with RSD may experience severe depression as a result of perceived rejection.

What if I suspect that I may have RSD?

If you suspect that you may have RSD, there’s a few routes you can take:

  • Talk to a healthcare provider in order to test for ADHD.
  • Find a therapist who you feel comfortable with – a therapist may help you develop new ways of thinking, and offer strategies/tools to manage RSD related symptoms.
  • Engage in self-care in order to care for your mind, body, and overall health.
  • Although there aren’t any official medications used to treat RSD, doctors may “off prescribe” certain medications, such as: stimulants, alpha 2 receptor agonists, and monoamine oxidase inhibitors (MOI). While MOI can help with depression, stimulants and alpha 2 receptors may help increase activity in specific brain areas related to emotions, which may help with RSD.

However, it’s extremely important to discuss with your primary healthcare provider before starting any kind of medication.

Sources: Rejection Sensitive Dysphoria (RSD). (2025, October 29). Cleveland Clinic

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